Fetal lung lesions: Management and outcome☆,☆☆,★
Section snippets
Material and methods
Case study review was performed for 175 fetal lung lesion patients (134 congenital cystic adenomatoid malformations and 41 extralobar pulmonary sequestrations) referred to the University of California, San Francisco Fetal Treatment Center from July 1, 1983, to June 30, 1995, and referred to the Center for Fetal Diagnosis and Treatment at the Children’s Hospital of Philadelphia from July 1, 1995, to December 31, 1997. All patients had evaluation of their sonographic findings at the University of
Congenital cystic adenomatoid malformation
There were 134 cases of congenital cystic adenomatoid malformation diagnosed between 17 weeks and 38 weeks’ gestation. Fourteen women underwent pregnancy termination: 12 fetuses had nonimmune hydrops, 1 had multiple structural abnormalities and hydrops, and 1 was otherwise normal. One hundred and twenty women elected to continue their pregnancies after the diagnosis was made: 101 women were managed expectantly, 13 women carrying hydropic fetuses underwent open fetal surgery, and 6 women
Comment
Congenital cystic adenomatoid malformation is characterized by an overgrowth of terminal respiratory bronchioles that form cysts of various sizes. Stocker et al11 defined 3 types of congenital cystic adenomatoid malformation (types I to III) primarily on the basis of cyst size. We have classified prenatally diagnosed congenital cystic adenomatoid malformation into 2 categories on the basis of gross anatomy and ultrasonographic findings.1 Macrocystic lesions contain single or multiple cysts that
Acknowledgements
We gratefully acknowledge the excellent patient care provided by the dedicated multidisciplinary teams at the Center for Fetal Diagnosis and Treatment at the Children’s Hospital of Philadelphia and the Fetal Treatment Center at the University of California, San Francisco.
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From The Center for Fetal Diagnosis and Treatment at the Children’s Hospital of Philadelphiaa and The Fetal Treatment Center at the University of California, San Francisco.b
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Reprint requests: N. Scott Adzick, MD, The Center for Fetal Diagnosis and Treatment, Children’s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104.
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