Role of nicotine dose and sensory cues in the regulation of smoke intake
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2016, International Review of NeurobiologyCitation Excerpt :This suggests that future IVSA models may need to look into coadministration studies for potential synergistic effects with nicotinic receptor antagonists and blocking other targets to have maximal efficacy in humans (Engleman, Rodd, Bell, & Murphy, 2008; Kuwabara, Heishman, Brasic, Contoreggi, et al., 2014). It has been well documented that sensory cues associated with tobacco smoking enhance the primary reinforcing effects of nicotine in smokers (Rose, Behm, & Levin, 1993). This has been shown to include the sensory effects in the larynx caused by particles in the tobacco smoke as well as paraphernalia associated with tobacco smoking such as the visual cues of cigarettes or the act of rolling up a cigarette before smoking.
Baseline impulsive choice predicts the effects of nicotine and nicotine withdrawal on impulsivity in rats
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