Research articleTheoretical validation of the respiratory benefits of helium-oxygen mixtures
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2012, Critical Care Nursing Clinics of North AmericaCitation Excerpt :Heliox, an inert gas composed of helium and oxygen, is a popular therapeutic adjunct in the care of severe bronchiolitis. As a low-density gas, heliox decreases the resistance of gas flow and reduces the work of breathing.89,91 In a meta-analysis of patients with bronchiolitis admitted to the PICU, Liet and colleagues92 (2010) found that heliox improved respiratory status after 1 hour of therapy.