Abstract
An 18-year-old man was referred to our hospital for further evaluation of a right anterior mediastinal tumor that measured 6 cm in diameter. Computed tomography-guided transcutaneous aspiration biopsy was performed, but no definitive diagnosis could be obtained. Because the tumor did not appear to be a high-grade malignant tumor, we undertook resection of the tumor to obtain a definitive diagnosis and provide appropriate treatment. Total thymectomy with tumor resection was performed through a median sternotomy. The tumor was solid, measuring 5.2 × 4.2 × 3.5 cm. The histological diagnosis was solitary fibrous tumor (SFT) arising from the mediastinum. Most extrathoracic SFTs appear to pursue a benign course, although careful long-term follow-up of these patients is necessary because the tumors have been reported to recur or metastasize in some cases.
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References
Klemperer P, Rabin CB. Primary neoplasm of the pleura; a report of five cases. Arch Pathol 1931;11:385–412.
De Perrot M, Fisher S, Brundler MA, Sekine Y, Keshavjee S. Solitary fibrous tumor of the pleura. Ann Thorac Surg 2002;74:285–293.
Kouki HS, Koletsis EN, Zolota V, Prokakis C, Apostolakis E, Dougenis D. Solitary fibrous tumor of the lung. Gen Thorac Cardiovasc Surg 2008;56:249–251.
Baliga M, Flowers R, Heard K, Siddiqi A, Akhtar I. Solitary fibrous tumor of the lung: a case report with a study of the aspiration biopsy, histopathology, immunohistochemistry, and autopsy findings. Diagn Cytopathol 2007;35:239–244.
De Raet J, Sacre R, Hoorens A, Fletcher C, Lamote J. Malignant giant solitary fibrous tumor of the mediastinum. J Thorac Oncol 2008;3:1068–1070.
Aoshima H, Oyama K, Ikeda T, Murasugi M, Onuki T, Sawada T. A case of intrapulmonary malignant solitary fibrous tumor with abnormal uptake on FDG-PET. Jpn J Lung Cancer 2008;48:51–55 (in Japanese with English abstract).
Guillou L, Fletcher JA, Fletcher CDM, Mandahl N. Extrapleural solitary fibrous tumor and hemangiopericytoma. In: Fletcher CDM, Unni Krishnan K, Mertens F, editors. WHO classification of tumors; pathology and genetics of tumors of soft tissue and bone. Lyon: IARC Press; 2002. p. 86–90.
England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura: a clinicopathologic review of 223 cases. Am J Surg Pathol 1989;13:640–658.
Hosono Y, Kohno T, Mun M, Makimoto Y, Hamamoto A, Yoshiya T, et al. A 3-ports-VATS resection of a solitary fibrous tumor in the mediastinum: a case report. Jpn J Chest Surg 2007;21:155–159 (in Japanese with English abstract).
Hasegawa T, Matsuno Y, Shimoda T, Hasegawa F, Sano T, Hirohashi S. Extrathoracic solitary fibrous tumors: their histological variability and potentially aggressive behavior. Hum Pathol 1999;30:1464–1473.
Schirosi L, Lantuejoul S, Cavazza A, Murer B, Yves Brichon P, Migaldi M, et al. Pleuro-pulmonary solitary fibrous tumors: a clinicopathologic, immunohistochemical, and molecular study of 88 cases confirming the prognostic value of de Perrot staging system and p53 expression, and evaluating the role of c-kit, BRAF, PDGFRs (alpha/beta), c-met, and EGFR. Am J Surg Pathol 2008;32:1627–1642.
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Suehisa, H., Yamashita, M., Komori, E. et al. Solitary fibrous tumor of the mediastinum. Gen Thorac Cardiovasc Surg 58, 205–208 (2010). https://doi.org/10.1007/s11748-009-0510-5
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DOI: https://doi.org/10.1007/s11748-009-0510-5