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Non-Tuberculous Mycobacteria: Classification, Diagnostics, and Therapy

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Part of the book series: Advances in Experimental Medicine and Biology ((NR,volume 944))

Abstract

Non-tuberculous mycobacteria (NTM) are species other than those belonging to the Mycobacterium tuberculosis complex and do not cause leprosy. NTM are generally free-living organisms that are ubiquitous in the environment. There have been more than 140 NTM species identified to-date. They can cause a wide range of infections, with pulmonary infections being the most frequent (65–90 %). There is growing evidence that the incidence of NTM lung diseases and associated hospitalizations are on the rise, mainly in regions with a low prevalence of tuberculosis. A crucial clinical problem remains the evaluation of NTM significance in relation to the disease, especially in regard to the colonization of the respiratory tract in patients with residual lesions after tuberculosis or bronchiectasis. Clinical and radiographic pictures of mycobacteriosis, as well as therapy, have often similarities to those of tuberculosis. The treatment regimen should be individualized. In addition to antituberculotics, antibiotics are used more frequently. The most common mycobacteria causing lung disease in Slovakia are Mycobacterium avium and Mycobacterium abscessus.

The original version of this chapter has been revised. An erratum to this chapter can be found at DOI 10.1007/978-3-319-44488-8_11

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The authors declare no conflicts of interest in relation to this article.

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Correspondence to I. Porvaznik .

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Porvaznik, I., Solovič, I., Mokrý, J. (2016). Non-Tuberculous Mycobacteria: Classification, Diagnostics, and Therapy. In: Pokorski, M. (eds) Respiratory Treatment and Prevention. Advances in Experimental Medicine and Biology(), vol 944. Springer, Cham. https://doi.org/10.1007/5584_2016_45

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