TABLE 1

Characteristics of included studies

StudyStudy designCountryMean age (years)Grouping (disease)Patients (n)Device used for unsupervised spirometryOutcomes reported
Bell 2022 [34]LongitudinalAustralia37Suppurative lung disease (CF)74Air Next (NuvoAir)FEV1, FVC
Broos 2018 [35]LongitudinalThe Netherlands43Interstitial lung disease (pulmonary sarcoidosis)21MicroDiary (CareFusion)FVC
Cheng 2016 [36]LongitudinalUSA51#Transplant (haematopoietic cell transplantation)571KoKo Peak Pro6 (Ferraris Respiratory) or PiKo-6 (Pulmonary Data Services)FEV1, FVC
Edmondson 2020 [37]Single day cross-overUK and Canada10#Suppurative lung disease (CF)67Lung Monitor BT SMART(Vitalograph)FEV1
Finkelstein 1993 [38]LongitudinalUSA50Transplant (lung transplant)18Advanced Medical Systems Inc.FEV1, FVC
Finkelstein 2000 [19]LongitudinalUSA42Obstructive airways disease (Asthma)32V2120 (Vitalograph)FEV1, FVC, FEF25–75%, PEF
Gerzon 2020 [30]Single day cross-overNetherlandsCF 9 Asthma 10Suppurative lung disease (CF) and obstructive airways disease (asthma)CF 36
Asthma 81
AM2+ (CareFusion)FEV1
Huang 2021 [39]LongitudinalUK41Obstructive airways disease (asthma)12mSpirometer (Cohero Health)FEV1
Kerwin 2019 [40]LongitudinalUSAN/AObstructive airways disease (asthma)21AM3 (eResearch Technology)FEV1
Khan 2022 [41]LongitudinalUK70Interstitial lung disease (interstitial lung disease)82Spirobank Smart (MIR)FEV1
Lindgren 1997 [42]LongitudinalUSA48Transplant (lung transplant)77PFM-H100 (Telemedical Inc.)FEV1, FVC
Marcoux 2019 [43]LongitudinalCanada73Interstitial lung disease (idiopathic pulmonary fibrosis)20Spirometer (PMD Healthcare)FVC
Moor 2018 [44]LongitudinalThe Netherlands71Interstitial lung disease (idiopathic pulmonary fibrosis)10Spirobank Smart (MIR)FEV1, FVC
Moor 2019 [45]LongitudinalThe Netherlands53#Interstitial lung disease (pulmonary sarcoidosis)10Spirobank Smart (MIR)FEV1, FVC
Moor 2020a [46]LongitudinalThe Netherlands70#Interstitial lung disease (idiopathic pulmonary fibrosis)46Spirobank Smart (MIR)FVC
Moor 2020b [47]LongitudinalThe Netherlands68#Interstitial lung disease (interstitial lung disease)50Spirobank Smart (MIR)FVC
Moor 2021 [48]LongitudinalNetherlands60Interstitial lung disease (interstitial lung disease)10Spirobank Smart (MIR)FVC
Morlion 2002 [49]LongitudinalBelgium33Transplant (lung transplant)22Microloop II (MicroMedical)FEV1, FEF25–75%
Mortimer 2003 [50]LongitudinalUSA9Obstructive airways disease (asthma)92EasyOne (NDD Medical)FEV1, FVC, FEF25–75%, PEF
Odisho 2021 [51]LongitudinalUSAN/ATransplant (lung transplant)311Spirometer (Not reported)FEV1
Paynter 2021 [52]LongitudinalUSA27Suppurative lung disease (CF)135AM2+ (ERT Inc.)FEV1
Rodriguez-Roisin 2016 [53]LongitudinalGlobal64Obstructive airways disease (COPD)2488EasyOne (NDD Medical)FEV1
Russell 2016 [54]LongitudinalUK67Interstitial lung disease (idiopathic pulmonary fibrosis)50Microspirometer (CareFusion)FEV1, FVC
Shakkottai 2018 [55]LongitudinalUSA16Suppurative lung disease (CF)39Spiro PD (PMD Healthcare)FEV1
Sheshadri 2020 [56]LongitudinalUSA55#Transplant (haematopoietic cell transplantation)82GoSpiro (Monitored Therapeutics)FEV1, FVC
Turner 2021 [57]LongitudinalUSA59#Transplant (haematopoietic cell transplantation)46GoSpiro (Monitored Therapeutics)FEV1, FVC
Veit 2020 [58]LongitudinalGermany63Interstitial lung disease (interstitial lung disease)47mySpirosense (PARI)FVC
Wijbenga 2020 [59]LongitudinalThe Netherlands67Transplant (lung transplant)10Spirobank Smart (MIR)FEV1, FVC

Disease was classed as the predominant condition in the study population. CF: cystic fibrosis; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of the FVC; PEF: peak expiratory flow; COPD: chronic obstructive pulmonary disease. #: median age reported; : studies in children (Kerwin et al. [40] reports outcomes of a subanalysis of 12–17-year-olds).