TABLE 2

Selected features associated with 2-year survival derived from patients with COPD

FeatureFrequency2-year survivalCohort's median age, years
BODE score >782/469 (17%) [10],
139/625(23%) [11]
75% [11], 70% [11]64 [10], 66 [11]
Resting hypoxaemia (PO2 ≤55 mmHg)81/175 LTx referrals (46%) [12]50% (COPD) to 70% (α-1 AD) [13]56 [12], 63–73 [13]
Hypoxaemia on exertion (SpO2 <88%) without resting hypoxaemia33/173 (19% in patient using oxygen) [14]80% [15, 16]56 [14], 68 [16]
Home noninvasive ventilation147/402 LTx referrals(36%) [12]65% [17, 18]65 [17], 67 [18]
Exacerbation with hypercapnia325/4343 (7%) [19, 20]51% [21], 35% [22], 47% [23]59 [21], 69 [22], 63 [23], 70 [19, 20]
≥1 exacerbation with hospitalisation105/304 (34%) [24]70% [24]69 [24]
FEV1 <20%69/1033 (7%) [25]80% [25]63 [25]
Mean pulmonary artery pressure ≥35 mmHg16/409 (4%) [26],
44/4305 (6%) [27]
70% [26], 58% [27]54 [26], 59 [27]

BODE: body mass index, obstruction, dyspnoea and exercise capacity score; PO2: oxygen tension; SpO2: peripheral oxygen saturation; FEV1: forced expiratory volume in 1 s; LTx: lung transplantation; α-1 AD: α-1 antitrypsin deficiency.