TABLE 1

Inclusion and exclusion criteria

InclusionExclusion
PopulationPatients (adults or children) with confirmed COVID-19 based on RT-PCR or clinically highly suspect casesStudies which only referenced “COVID-19” broadly
ExposureSevere asthma diagnosed by clinicians or by validated or nonvalidated guidelinesSelf-reported asthma patients
ComparatorPatients (adults or children) with confirmed COVID-19 based on RT-PCR and without pre-existing severe asthma diagnosisStudies without any comparator
Outcome1) Risk of hospitalisation for people with severe asthma
2) Risk of ICU admission/mechanical ventilation for people with severe asthma
3) Risk of death for people with severe asthma
1) Asymptomatic or mild to moderate COVID-19 symptoms
2) Studies focusing only on the pathophysiology of COVID-19 in asthma or severe asthma
Study designStudies of any design besides those specified in the exclusion criteriaModelling studies, opinion pieces, editorials, reviews and laboratory studies
Geographical locationStudies conducted in any country or countriesNo restrictions based on geographical location

COVID-19: coronavirus disease 2019; RT-PCR: reverse transcriptase PCR; ICU: intensive care unit.