Simplified definitions
Entity | Population | Diagnostic criteria | Definition | |
ILA | Only individuals without known or suspected ILD# | Clinical-radiological entity | Incidental finding of CT abnormalities affecting more than 5% of any lung zone | |
Early ILD | Pre-clinical ILD | Individuals at risk for ILD | Clinical-radiological-pathological entity | Any ILD in asymptomatic patients with preserved lung function |
Subclinical ILD | Individuals NOT at risk for ILD | |||
Mild ILD | All individuals | Clinical-radiological-pathological entity | Any clinically significant ILD with minor symptoms and/or trivial PFT abnormalities |
ILA: interstitial lung abnormalities; ILD: interstitial lung disease; CT: computed tomography; PFT: pulmonary function test. #: abnormalities identified during screening for ILD in high-risk groups (e.g. those with rheumatoid arthritis, systemic sclerosis or familial ILD) are not considered as ILA because they are not incidental.