Factors associated with mortality in patients with HP

Intrinsic factorsOlder age
Male sex
Genetic predisposition
ExposuresUnidentifiable inciting antigen
Duration of exposure to inciting antigen
History of smoking
PhysiologyLow FVC
Decline in FVC
Lower BAL lymphocytosis
RadiologyPresence of fibrosis on HRCT
Extent of fibrosis on HRCT
UIP pattern on HRCT
HistologyUIP pattern
Fibrotic NSIP pattern

BAL: bronchoalveolar lavage; DLCO: diffusing capacity of the lungs for carbon monoxide; FVC: forced vital capacity; HRCT: high-resolution computed tomography; NSIP: non-specific interstitial pneumonia; UIP: usual interstitial pneumonia.