TABLE 1

Studies showing the prevalence of perioperative complications after non-cardiac surgery in pulmonary hypertension (PH) patients

Authors, year [ref.]Study typeNPH diagnosisAetiology of PHGAMajor surgeryMortalityMorbidity
Ramakrishna et al. 2005 [34]Retrospective no control145TTE or RHCGroup 1 45%
Group 3 19%
Group 4 8%
100%79%7%42%
Minai et al. 2006 [36]Retrospective no control28#RHCGroup 1 100%79%86%18%19%
Lai et al. 2007 [37]Retrospective no control62TTEGroup 1 18%
Group 2 21%
Group 3 21%
58%65%9.7%24%
Price et al. 2010 [29]Retrospective no control28RHCGroup 1 72%
Group 4 28%
50%57%7%29%
Memtsoudis et al. 2010 [38]Retrospective 1:3 matching with no-PH3543Not specifiedNANA100% (THR/TKR)2.4% (versus 0.9% in no-PH)NA
Kaw et al. 2010 [33]Retrospective controlled96RHCGroup 1 12%
Group 2 40%
Group 5 48%
100%48%1%28%
Meyer et al. 2013 [32]Prospective no control114RHCGroup 1 100%82%69%3.5%6.1%
Seyfarth et al. 2015 [39]Retrospective no control31RHCGroup 1 74%
Group 3 10%
Group 4 16%
77%100%3%25%
Smilowitz et al. 2019 [40]Retrospective controlled3500VariableGroup 1 100%NAAll types8.3%12.9%
Deljou et al. 2019 [41]Retrospective no control196RHCGroup 1 74%
Group 3 14%
Group 4 13%
100%45%3%27%

GA: general anaesthesia; NA: not available; RHC: right heart catheterisation; TTE: transthoracic echocardiography; THR: total hip replacement; TKR: total knee replacement. #: N=21 patients underwent 28 procedures. : 149 (4.3%) patients had RHC, others were reported PAH.