Effects of anaesthetic agents, vasopressors and inotropes on pulmonary vasculature and right ventricle function [42, 47, 96, 97, 100, 101]

AgentsmPAPPVRRV contractility
Anaesthetic agents
 Nitrous oxide↑↑↑↑
 Thiopental sodium
 Dobutamine↑, ↔, ↓#↑↑

↑ Increase; ↑↑ marked increase; ↓ reduction; ↓↓ marked reduction; ↔ no effect. mPAP: mean pulmonary arterial pressure; PVR: pulmonary vascular resistance; RV: right ventricle. #: Conflicting data about the effect of dobutamine in PVR. Dobutamine decreases PVR at low dose (<5 µg·kg−1·min−1), no effect at median dose of 10 µg·kg−1·min−1 and increases PVR at higher dose, more than 15 µg·kg−1·min−1 [47, 102104].