An overview of the values of the area under the receiver operating characteristics curve (AUCROC) per matrix and marker as reported by the meta-analyses
| Serum | Plasma | PE | |
| Mesothelin | 0.81 (0.79–0.83) | 0.86 (0.79–0.92) | 0.83 (0.81–0.85) |
| MPF | 0.78 (0.73–0.83) | ||
| HMGB1 | 0.88 (0.80–0.96) | ||
| ILK | 0.79 (0.59–0.99) | ||
| OPN | 0.66 (0.56–0.75) | 0.69 (0.63–0.75) | |
| TRX | 0.77 (0.68–0.87) | ||
| Fibulin3 | 0.91 (0.86–0.97) | 0.68 (0.50–0.87) | |
| CEA | 0.55 (0.21–0.89) | ||
| CYFRA 21–1 | 0.73 (0.67–0.78) | ||
| HA | 0.78 (0.73–0.82) | ||
| miR 126 | 0.80 (0.68–0.91) |
MPF: megakaryocyte potentiating factor; HMGB1: high-mobility group box 1; ILK: integrin-linked kinase; OPN: osteopontin; PE: pleural effusion; TRX: thioredoxin; CEA: carcinoembryonic antigen; CYFRA 21-1: cytokeratin 19 fragments; HA: hyaluronan; miR: microRNA. The highest AUCROC per matrix are in bold, the highest AUCROC values per biomarker are underlined.