Clinical and biological characteristics of 48 patients with immunoglobulin G4-related disease (IgG4-RD) thoracic involvement
| Characteristic | Patients (n=48) |
| Demographic data | |
| Male | 39 (81) |
| Median age at onset (years) | 60 (23–83) |
| Median diagnostic delay (months) | 6 (1–240) |
| Smoker or former smoker | 9 (19) |
| History of atopy | 18 (37) |
| Organ involvement of IgG4-RD | |
| Median number of organs affected | 3 (1–6) |
| Lymph nodes | 30 (62.5) |
| Pancreatitis | 15 (31.2) |
| Tubulointerstitial nephritis | 15 (31.2) |
| Sialadenitis | 15 (31.2) |
| Retroperitoneal fibrosis | 10 (20.8) |
| Sclerosing cholangitis | 10 (20.8) |
| Aortitis | 8 (16.6) |
| Dacryoadenitis | 6 (12.5) |
| Prostatitis | 3 (6.2) |
| Biological characteristics | |
| Elevated serum IgG (>1400 mg·dL−1) | 43 (89.5) |
| Elevated serum IgG4 (>135 mg·dL−1) | 43 (89.5) |
| Elevated serum IgG4 >2xN | 32 (66.7) |
| Median serum IgG4 level (mg·dL−1) | 430 (23–2040) |
| Hypocomplementaemia | 13 (27) |
| Elevated CRP (>5 mg·L−1) | 39 (81.2) |
| Positive ANA (>1/160) | 9 (18.8) |
Data are presented as n (%) or median (range). ANA: antinuclear antibody; CRP: C reactive protein.