TABLE 1

Descriptive summary of selected studies

First author [ref.]DesignGroupSample size nAge yearsBMI Kg·m−2FEV1 % predDLCO % predPaO2 mmHgmPAP mmHg
Studies without lung transplant candidates
 Holverda [21]RetrospectiveCOPD-nonPH1566±1025±349±1950±1374.3±10.518±3
COPD-PH1064±1122±462±3137±1457.0±15.033±6
 Boerrigter [18]Cross-sectionalCOPD-nonPH2462±1425±249±1850±1471±1118.5±3.1
COPD-PH2367±926±451±1938±1557±1139.1±11.9
 Skjørten [28]Cross-sectionalCOPD-nonPH7164.6±625±447±1657±1974±918±3.5
COPD-PH2261±825±629±930±1461±1128.7±4.6
 Xiong [29]ProspectiveCOPD-nonPH9864.9 ±7.123.8±5.944.9±20.2NR60.8±16.819.7±20.5
COPD-PH8267.3±6.720.1±6.042.3±22.7NR48.1±16.032.0±20.6
 Blanco [10]Cross-sectionalCOPD-nonPH10968±828±551±1659±1772±10NR
COPD-PH6566±826±432±1140±1567±12NR
Studies with lung transplant candidates
 Thirapatarapong [11]RetrospectiveCOPD-nonPH6759 (55–61)23±3.920±728 (20–43)72.7±1720.9±3.1
COPD-PH3159 (57–62)22.7±418±625 (20–26)67.0±2030.2±5.0
 Adir [12]RetrospectiveCOPD-nonPH2061.1±4.422.1±4.824.9±8.935.2±17.3NR20.2±2.2
COPD-PH2459.4±6.325.5±4.725.9±11.639.2±15.9NR28.6±2.7

Data are presented as mean±sd or median (interquartile range), unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide; PaO2: arterial oxygen tension; mPAP: mean pulmonary arterial pressure; PH: pulmonary hypertension; NR: not reported.