Corticosteroids in community-acquired pneumonia (CAP) versus coronavirus disease-2019 (COVID-19)
| CAP | COVID-19 | |
| Severity | IDSA/ATS severe CAP [11] | Severe acute respiratory failure# |
| Timing | First 24 h | First 24 h |
| Type of steroids and dosage | Prednisone (50 mg daily) Methylprednisolone (40–80 mg daily) Dexamethasone (5 mg daily) | Dexamethasone (6 mg daily) Hydrocortisone (200 mg daily) |
| Duration | 5–8 days | 7 days |
| Outcome | Decrease treatment failure and mortality | Decrease mortality |
| Harms | Increased readmission in one study | CAPA? |
IDSA: Infectious Diseases Society of America; ATS: American Thoracic Society; CAPA: COVID-19-associated pulmonary aspergillosis. #: as defined in the RECOVERY trial [58].