TABLE 1

Summary of study characteristics and health outcomes instruments

Study design	Study location	Patients n			Recruitment duration	Instrument/ measurement	Reported health outcome	[Ref.]
Study design	Study location	LTBI	TB	Without TB infection	Recruitment duration	Instrument/ measurement	Reported health outcome	[Ref.]
Longitudinal	TB clinics, MCI and JGH, Canada	105	48	110	June 2008–October 2011 (40 months)	1) SF-36 → SF-6D utilities 2) SG	HRQoL [19] Health utilities [18]	[18, 19]
Prospective cohort	Broward or Palm Beach County Health Dept, Florida, USA	90			August 2005–July 2007 (24 months)	1) Stigma scale from EMIC for Tuberculosis in Haitian Populations	Stigma	[20]
Cross-sectional	TB clinic, MCI, Canada	35	22		1 September 1999–30 September 2000 (13 months)	1) VAS 2) SG 3) SF-36 4) EQ-5D	HRQoL	[21, 22]
Qualitative	TB-OPD, Karolinska University Hospital, Solna, Sweden	16			December 2017–June 2018 (7 months)	Interview guide	Treatment experience	[23]
Longitudinal	TB clinic, British Columbia Centre for Disease Control, Canada	102	104		2005–2006 (12 months)	1) SF-36 v2→SF-6D utilities 2) BDI 3) HUI2, HUI3 4) VAS	HRQoL [24] Health utilities [25]	[24, 25]
Retrospective	TB registries, 20 different sites in the USA	7 282	3853		1993–31 December 2002 (9 years)	1) Mortality risk	Mortality	[26]
Retrospective	TB clinic, TCPH, Texas, USA	210	107		7 July 2005–7 November 2006 (16 months)	1) SGRQ	HRQoL [27] QALY [22]	[27, 28]
Cross-sectional	Infectious disease or paediatric clinics, Karolinska University Hospital, Sweden	108		19 415	September 2017–June 2018 (10 months)	1) EQ-5D 2) RHS-15	HRQoL	[29]
Cross-sectional	Dispensary of TB Kayseri, Turkey	108	196	196	15 September 2003–15 September 2004 (12 months)	1) SF-36 2) BDI	HRQoL	[30]

LTBI: latent tuberculosis infection; TB: tuberculosis; MCI: Montreal Chest Institute; JGH: Jewish General Hospital; SF-36: 36-item Short-Form Health Survey; SF-6D: Short-Form Six-Dimension; SG: standard gamble tasks; HRQoL: health-related quality of life; EMIC: Explanatory Model Interview Catalogue; VAS: visual analogue scale; EQ-5D: EuroQol-5 dimensions; TB-OPD: Tuberculosis outpatient department; SF-36 v2: 36-item Short-Form Health Survey version 2; BDI: Beck Depression Inventory; HUI2: Health Utilities Index Mark 2; HUI3: Health Utilities Index Mark 3; TCPH: Tarrant County Public Health; SGRQ: St George's Respiratory Questionnaire; QALY: quality-adjusted life year; RHS-15: Refugee Health Screener-15.