American College of Rheumatology/European League against Rheumatism classification criteria for primary Sjogren syndrome
| Item | Weight/score |
| Labial salivary gland with focal lymphocytic sialadenitis and focus score ≥1 foci·4 mm−2 | 3 |
| Anti-SSA/Ro-positive | 3 |
| Ocular staining score ≥5 (or van Bijsterveld score ≥4) in at least one eye | 1 |
| Schirmer's test ≤5 mm in 5 min in at least one eye | 1 |
| Unstimulated whole saliva flow rate ≤0.1 mL·min−1 | 1 |
A patient can be classified as having primary Sjogren syndrome with a score of ≥4 and without any of the conditions listed as exclusion criteria. Exclusion criteria include prior diagnosis of any of the following conditions: history of head and neck radiation treatment; active hepatitis C infection; AIDS; sarcoidosis; amyloidosis; graft-versus-host disease; immunoglobulin G4-related disease [12].