TABLE 3

Validated daily diaries and questionnaires for measurement of control of asthma symptoms

TestTargetMeasureReportSuggested MCID
Pediatric Asthma Caregiver DiaryCaregivers of 2–5 year-old childrenDaily diary completed by caregivers:

  • daytime symptoms: activity limitation, need for urgent care, SABA use (7 items; from 0 to 5-point scale);

  • night-time symptoms: impact on caregiver, SABA use (3 items; from 0 to 5-point scale)

  • Mean daytime and night-time symptoms

Not established
Daytime Symptom Diary Scale and Nocturnal Diary ScaleAdult patientsDaily diary completed by adult patients:

  • daytime symptoms (4 items; from 0 to 6-point scale);

  • nocturnal awakening (1 item; from 0 to 3-point scale)

  • Mean scores (daily, weekly)

  • Change over time is the difference between mean score from a 2-week baseline and a 2-week subsequent period

Not established
Asthma Symptom Utility IndexAdult patientsRetrospective questionnaire on previous 2 weeks:

  • 11 items divided accordingly by the frequency and severity of asthma symptoms (8 items) and side-effects (3 items)

  • Scoring uses a table for converting patient reported data into utilities (range 0–1)

  • Mean scores

  • Change in mean scores

0.09 points
Asthma Control QuestionnaireAdult patients
It has been also fully validated for children aged >6 years: 11–17 years self-administered adult version; 6–10 years interviewer-administered version; it has not been validated in children aged <6 years old		Retrospective questionnaire to measure the adequacy of asthma control and change in asthma control which occurs either spontaneously or as a result of treatment,
7 items divided according to the frequency and severity of daytime and night-time asthma symptoms (5 items), SABA use (1 item) and FEV1 (1 item)		Scoring uses a table for converting patient reported data into utilities

  • Score range between 0 (totally controlled) and 6 (severely uncontrolled)

  • Change in mean scores

0.5 points
Asthma Control TestPatients aged ≥12 yearsMonthly retrospective questionnaire:

  • Asthma composite score of 5 items on symptoms and daily functioning

  • From 1 to 5-point scale (for symptoms and activities: 1=all the time, to 5=not at all; for asthma control rating: 1=not controlled at all, to 5=completely controlled)

  • Score range from 5 (poor control) to 25 (complete control)

  • Asthma Control Test score >19 indicates well-controlled asthma

For adults: 3 points
For patients aged 12–18 years: 2 points
Childhood Asthma Control TestChildren/caregivers of 4–11 year-old childrenMonthly retrospective questionnaire:

  • Asthma composite score of 7 items (1–4: children; 5–7: caregivers) on symptoms and daily functioning

  • From 0 to 3-point scale for items 1–4 and from 0 to 5-point scale for items 5–7

  • Score range 0–19: asthma symptoms not controlled

  • Score range 20–27: well-controlled asthma

2 points

MCID: minimal clinically important difference; SABA: short-acting β-agonist; FEV1: forced expiratory volume in 1 s.