TABLE 3

Comparison of 10 currently available BNP/NT-proBNP POCT devices

DeviceBNP/
NT-proBNP
Time to resultSubjects nCorrelation with clinical laboratory (unless specified)[Refs]
Quidel Triage BNP Test (formerly Alere Heart Check)BNP∼15 min22600.95 (versus Siemens ADVIA Centaur) [88]Maisel [87] (n=1586)
Ro [88] (n=250)
Lang [99] (n=150)
Monfort [84] (n=163)
De Vecchis [60] (n=111)
Quidel Triage NT-proBNP Test (formerly Alere NT-proBNP)NT-proBNP∼20 min1000.94 (versus Roche cobas 8000)Khezri [98]
Roche cobas h 232NT-proBNP≤12 min18870.97 (versus Roche cobas e602) [91]Bertsch [92] (n=1591)
Gils [90] (n=202)
Hex [91] (n=94)
Philips Minicare BNPBNP≤10 min3470.92 (versus Siemens ADVIA Centaur)Reenen [93]
Abbott i-STATBNP∼9 min4000.98 (versus Siemens ADVIA Centaur) [88]Shah [94] (n=150)
Ro [88] (n=250)
Mitsubishi PATHFASTNT-proBNP<17 min3260.99 (versus Roche Elecsys) [96]Peetz [96] (n=90)
Zaninotto [70] (n=236)
Radiometer AQT90 FLEXNT-proBNP11–21 min77>0.99 (versus Roche Elecsys 2010)Lepoutre [97]
Response Biomedical RAMP NT-proBNPNT-proBNP∼15 min5400.98 (versus Roche Elecsys 2010)Lee-Lewandrowski[89]
Sekisui Medical RapidpiaBNP<15 min570.93 (versus SHIONOSPOT)#Ishida [100]
Shionogi SHIONOSPOTBNP∼16 min570.93 (versus Rapidpia)#Ishida [100]

BNP: B-type natriuretic peptide; NT-proBNP: N-terminal prohormone of BNP; POCT: point-of-care testing. #: Sekisui Medical Rapidpia and Shionogi SHIONOSPOT are both POCT devices compared with each other in this study.