TABLE 1

Commercially available devices: specifications and characteristics

Eco Medics AG Exhalyzer DInnovision InnocorNdd EasyOne Pro Lab
Measurement principleUltrasonic transit in timePhotoacoustic spectroscopyUltrasonic transit in time
Overall design of set-upOpen circuit wash-in and washout design using bias flowClosed, re-breathing circuit wash-in designed with CO2 scrubber to prevent CO2 accumulation
Open circuit washout design
Open circuit washout design using bias flow
Inert gas assessedN2 and SF6 MBW options availableSF6N2
Bias flow gas mixture usedMedical air and 100% O2 required for N2-based MBW
Wash-in SF6/O2/N2 mixture for SF6-based MBW sourced by individual user from local supplier
Wash-in gas available as licensed
SF6 gas mixture supplied by Innovision
Medical air and 100% O2 required for N2-based MBW
ApplicationAdults, children and infants >3 kgAnyone capable of following instructions from the operatorAdults and children aged >4 years and >18 kg
Additional commentsSemiportable
Operator interface through linked laptop
Phase III slope analysis for Scond and Sacin is integral to the software
Self-contained, portable
User interface, LCD touch screen
Phase III slope analysis not available
Self-contained, portable
Operator interface, LCD touch screen
Phase III slope analysis not routinely implemented; research software available

SF6: sulphur hexafluoride; MBW: multibreath washout; Scond: usual index of ventilatory inhomogeneity in the conducting airways; Sacin: index of ventilatory inhomogeneity within the acinar airways.