TABLE 2

Framework to classify review level evidence

Sufficient review level evidence to either support or discount the effectiveness of an intervention
 Clear and consistent statement from one or more core reviews based on multiple robust studies, or
 Consistent evidence across multiple robust studies within one or more core reviews, in the absence of a clear and consistent statement in the review(s)
Tentative review level evidence to either support or discount the effectiveness of an intervention
 A cautious statement from one or more core reviews based on consistent evidence from a small number of robust studies, or
 Consistent evidence from a small number of robust studies or multiple weaker studies within one or more core reviews, in the absence of a clear and consistent statement in the review(s), or
 Conflicting evidence from one or more core reviews, with the stronger evidence weighted towards one side (either supporting or discounting effectiveness) and a plausible reason for the conflict, or
 Consistent evidence from multiple robust studies within one or more supplementary review, in the absence of a core review
Insufficient review level evidence to either support or discount the effectiveness of an intervention
 A statement of insufficient evidence from a core review, or
 Insufficient evidence to either support or discount the effectiveness of an intervention (either because there is too little evidence or the evidence is too weak), in the absence of a clear and consisten statement of evidence from a core review(s), or
 Anything less than consistent evidence from multiple robust studies within one or more supplementary reviews.
No review level evidence
 No core or supplementary reviews of the topic identified, possibly due to a lack of primary studies