TABLE 1

Clinical features of patients with obesity hypoventilation syndrome based on an aggregated sample of 757 patients from 15 studies

Clinical featuresMean (range)
Age years52 (42–61)
Male %60 (49–90)
Body mass index kg·m−244 (35–56)
Neck circumference cm46.5 (45–47)
pH7.38 (7.34–7.40)
Arterial PCO2 mmHg53 (47–61)
Arterial PO2 mmHg56 (46–74)
Serum bicarbonate mEq·L−132 (31–33)
Haemoglobin g·dL−115
Apnoea–hypopnoea index66 (20–100)
SpO2 nadir during sleep %65 (59–76)
Per cent sleep time SpO2 <90%50 (46–56)
FVC % predicted68 (57–102)
FEV1 % predicted64 (53–92)
FEV1/FVC0.77 (0.74–0.88)
Medical Research Council
Dyspnoea class 3 or 4 %
69
Epworth sleepiness scale score14 (12–16)

PCO2: carbon dioxide tension; PO2: oxygen tension; SpO2: arterial oxygen saturation measured by pulse oximetry; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s. Reproduced from [1] with permission from the publisher.