Summary of frequency with which trials met their end-points comparing active treatment with placebo or control in each end-point category

End-point groupExacerbation-relatedMicrobiologySputum-relatedLung functionHRQoLBiomarkers (blood and sputum)Other
Primary end-points3/7#5/51/41/41/52/41/2
Accumulative end-points9/196/125/133/199/233/122/9

Data are presented as n/N. HRQoL: health-related quality of life. #: most commonly used primary end-point; : most commonly used end-point (primary and secondary).