Diagnostic criteria for neurofibromatosis type 1 (NF1) [9]

Two or more of the criteria below are required for diagnosis:
 Six or more café au lait macules (>0.5 cm in children or >1.5 cm in adults)
 Two or more cutaneous or subcutaneous neurofibromas or one plexiform neurofibroma
 Axillary or groin freckling
 Optic pathway glioma
 Two or more Lisch nodules (iris hamartomas seen on slit lamp examination)
 Bony dysplasia (sphenoid wing dysplasia, bowing of long bone±pseudoarthrosis)
 First-degree relative with NF1