TABLE 3

Comparison of serological domains

ABCDA versus BA versus CB versus CA versus DB versus DC versus D
Patients n144565798
Serological domain91.791.193nrnsnsns
 ANA77.648.282.447.9<0.0001ns0.0001<0.0001ns<0.0001
 RF ≥40 IU1310.7728.5#nsnsns0.00020.010.0001
 ACPA4.710.78.815.3nsnsns0.004nsns
 Anti-Sdna7.21.85.26.2nsnsnsnsnsns
 Anti-Ro/SS-A16.642.98.818.3<0.0001ns<0.0001ns0.001ns
 Anti-La/SS-B2.95.41.77.1nsnsnsnsnsns
 Anti-RNP4.916.109.10.008ns0.001nsns0.01
 Anti-Smith1.58.904.10.01ns0.02nsnsns
 Anti-Scl7031.85.28.1nsnsns0.07nsns
 Anti-tRNA synthetase0.735.715.813.2<0.00010.050.01<0.00010.001ns
 Anti-PM/Scl1.85.2nrns
 Anti-MDA-500nrns

Data are presented as mean±sd or %, unless otherwise stated. Bold represents the highest significant value. A: Oldham et al. [18]; B: Chartrand et al. [22]; C: Ahmad et al. [23]; D: Ito et al. [24]; ANA: antinuclear antibodies; RF: rheumatoid factor; ACPA: anti-citrullinated protein antibodies; SS: Sjögren syndrome; RNP: ribonucleoprotein; PM/Scl: polymyositis/systemic sclerosis; MDA: melanoma differentiation antigen; nr: not reported; ns: nonsignificant. #: RF >60 IU.