MUC5B | 11p15 | Encodes glycoproteins in airway mucus | [87–99] |
TOLLIP | 11p15 | Regulates innate immunity through Toll-like receptors (TLRs) | [91, 100] |
TERT/TERC | 5p15.33/3q26 | Maintains telomere length | [101–108] |
TLR3 | 4q35 | Regulates innate immunity | [109, 110] |
SFTPC | 8p21 | Facilitates surfactant function and transport and innate defence | [111, 112] |
ABCA3 | 16p13.3 | ATP-binding cassette involved in surfactant production | [113] |
SFTPA2 | 10q22.3 | Facilitates surfactant function and transport and innate defence | [114] |
CSF2RA and CSF2RB | Xp22.33, Yp11.2 and 22q12.3 | Reduce granulocyte−macrophage colony-stimulating factor receptor signalling | [115, 116] |