TABLE 2

Technical factors that may affect volume measurement

Effects on volumetry
Section thicknessVolume overestimation with thick sections [40, 68, 69, 86–89]
Overlapping reconstructionVolume overestimation with non-overlapping sections [90, 91]
PitchLow accuracy with high pitch mode [92]
Reconstruction algorithmsEasier nodule sampling with high spatial frequency algorithms [86, 89, 91, 93]
Volume overestimation with high spatial frequency algorithms [90, 94, 95]
Intravenous contrast mediumVolume overestimation [95–97]
Scanner typeDifferences in volume estimation [50, 86, 98]
Higher accuracy with helical CT scanner [98]
Low radiation doseLow accuracy [76, 99, 100]
Iterative reconstructionBetter performance [101–112]
Manual versus semi/automated methodReduced observer variability with automated system [113, 114]
Manual interaction reduces bias due to the software performance [55, 115]
Software and algorithms packageDifferences in volume estimation [57, 67, 116–118]

CT: computed tomography.