Relationship between nodule size, expressed as diameter and volume, and growth rate, expressed as volume doubling time (VDT), with the prevalence of malignancy
Prevalence of malignancy % | ||
NELSON screening study [8] | Literature review [9] | |
Diameter mm | ||
<5 | 0.4 | 0–1 |
5–10 | 1.3 | 6–28 |
≥10 | 15.2 | 33–60 |
≥20 | 64–82 | |
Volume mm3 | ||
≤100 | 0.6 | |
100–300 | 2.4 | |
≥300 | 16.9 | |
VDT days | ||
≥600 | 0.8 | |
400–600 | 4 | |
≤400 | 9.9 |
Data from [8, 9].