TABLE 1

Relationship between nodule size, expressed as diameter and volume, and growth rate, expressed as volume doubling time (VDT), with the prevalence of malignancy

Prevalence of malignancy %
NELSON screening study [8]Literature review [9]
Diameter mm
 <50.40–1
 5–101.36–28
 ≥1015.233–60
 ≥2064–82
Volume mm3
 ≤1000.6
 100–3002.4
 ≥30016.9
VDT days
 ≥6000.8
 400–6004
 ≤4009.9

Data from [8, 9].