TABLE 2

Studies comparing lobectomy and segmentectomy functional consequences

First author [ref.]	Year	Procedure	Patients n	Mean pre-operative FEV₁ % pred	PFT delay months	Mean FEV₁ change %
Ginsberg [4]	1995	Lobectomy	71	93% patients >50%	6	−9.1
					12–18	−11.09
		Segmentectomy	67	93% patients >50%	6	−1.76^#
					12–18	−5.18^#
Takizawa [16]	1999	Lobectomy	40	105	0.5	−26.7
					12	−13.7
		Segmentectomy	40	109	0.5	−24.5^#
					12	−6.7^#
Keenan [8]	2004	Lobectomy	147	75	12	−10^¶
		Segmentectomy	54	55	12	−5^¶
Martin-Ucar [11]	2005	Lobectomy	12	44	3–6	−12
		Segmentectomy	11	45	3–6	+12^#
Harada [5]	2005	Lobectomy	45	74	2	−24^¶
					6	−18^¶
		Segmentectomy	38	75	2	−15^#,¶
					6	−12^#,¶
Okada [13]	2006	Lobectomy	168	2.32 L⁺	2	−16.8
		Segmentectomy	168	1.93 L⁺	2	−9.4
Kashiwabara [7]	2009	Lobectomy	47	107	6	Normal FEV₁: −18.9
						FEV₁ <70%: −12.8
		Segmentectomy	71	109	6	Normal FEV₁: −12.9^#
						FEV₁ <70%: −13.8
Saito [14]	2014	Lobectomy	126	77	1	−28
					6	−19
		Segmentectomy	52	78	1	−22
					6	−10^#
Hwang [6]	2015	Lobectomy	94	101	NA	−11.0
		Segmentectomy	94	102	NA	−8.9
Kim [9]	2015	Lobectomy	227	109	3	−13.6
					12	−8.49
		Segmentectomy	73	100	3	−4.84^#
					12	−1.74^#
Macke [10]	2015	Lobectomy	70	85	6–36	−8.2
		Segmentectomy	89	79	6–36	−4.3^#
Suzuki [15]	2016	Lobectomy	33	75	2	−29
					7–12	−11
		Segmentectomy	37	73	2	−19
					7–12	−12
Nomori [12]^§	2016	Segmentectomy	117	<2 seg: 105	7 (6–13)	<2 seg: −3^#
				≥2 seg: 114		≥2 seg: −10^#
				LUD: 117		LUD: −16
		Lobectomy	13	LUL: 114		LUL: −17

FEV₁: forced expiratory volume in 1 s; PFT: pulmonary function test; NA: not available. ^#: significant difference between lobectomy and segmentectomy; ^¶: calculated from data or extracted from figures; ⁺: absolute values in L given where no % pred values available; ^§: compared resections <2 segments (<2 seg), ≥2 segments (≥2 seg), of the left upper division (LUD) and left upper lobectomy (LUL).