Differential diagnosis of granulomatous lung diseases
| Infectious lung diseases | |
| Mycobacteria | Tuberculosis and nontuberculous mycobacteriosis |
| Fungal infection | Cryptococcus, Coccidioides, Histoplasma, Blastomyces and Aspergillus |
| Aspiration pneumonia | |
| Others | Syphilis, Hansen's disease (leprosy), tularaemia, cat scratch disease, parasitic infections and Whipple's disease |
| Noninfectious lung diseases | |
| Inflammatory | Sarcoidosis |
| Necrotising sarcoid granulomatosis | |
| Bronchocentric granulomatosis | |
| Inflammatory bowel disease | |
| Exposure/toxins | Hypersensitivity pneumonitis |
| Drugs (methotrexate, interferon, Bacillus Calmette-Guérin, infliximab, etanercept, leflunomide, mesalamine and sirolimus) | |
| Hot tub lung | |
| Berylliosis | |
| Talc | |
| Metals (aluminium and zirconium) | |
| Foreign body reaction | |
| Vasculitis | Granulomatosis with polyangiitis |
| Eosinophilic granulomatosis with polyangiitis | |
| Autoimmune diseases | Rheumatoid nodule |
| Malignancy | Sarcoid-like lesions |
| Lymphomatoid granulomatosis | |
| Others | Pulmonary Langerhans cell histiocytosis Granulomatous–lymphocytic interstitial lung disease |