Factors associated with increased risk of mortality in idiopathic pulmonary fibrosis
| At baseline | Level of dyspnoea |
| DLCO <40% predicted | |
| Desaturation <88% during 6MWT | |
| Peak V′O2 <8.3 mL·kg−1·min−1 on CPET | |
| Extent of honeycombing on HRCT | |
| Pulmonary hypertension | |
| Longitudinal factors | Increase in level of dyspnoea |
| FVC <10% of absolute value | |
| DLCO <15% of absolute value | |
| Worsening of fibrosis on HRCT |
Information from [9, 12]. DLCO: diffusion capacity of the lung for carbon monoxide; 6MWT: 6-min walk test; V′O2: oxygen uptake; CPET: cardiopulmonary exercise test; HRCT: high-resolution computed tomography; FVC: forced vital capacity.