Congenital heart disease and cardiovascular disease in individuals with Down syndrome
| Children | Atrioventricular septal defects (these are the most common in children with Down syndrome) Ventricular septal defects Atrial septal defects Patent ductus arteriosus Tetralogy of Fallot |
| Adults | Acquired valvular heart disease, including mitral prolapse and valvular regurgitation Low rates of atherosclerosis, myocardial infarction and stroke Reduced rate of hypertension and less coronary artery intima medial thickness |