Pathological findings in pulmonary oxygen toxicity and their changes in lung function parameters
| Pathological changes | Increase in parameter | Decrease in parameter |
| Interstitial oedema | VC, DLCO, CL,st | |
| Alveolar oedema | VC, DLCO, CL,st | |
| Pulmonary capillary fibrin thrombin | VC, DLCO, FeNO | |
| Loss of alveolar type 1 cell | VC, DLCO, CL,st | |
| Neutrophilic infiltration | FeNO | FeNO |
| Capillary endothelial lesions | VC, DLCO, CL,st | |
| Interstitial distention | DLCO | |
| Increase alveolar type 2 cells | CL,st | DLCO |
| Infiltration inflammatory cells | FeNO | |
| Haemorrhage | DLCO |
VC: vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; CL,st: static lung compliance; FeNO: exhaled nitric oxide fraction. Data from [58].