Reasons for exclusion at stage 2 on the basis of full text articles

Reason for exclusion at stage 2Number of articles (%)
Adverse experience inadequately measured (e.g. retrospectively)12 (24)
Does not follow a prospective/longitudinal design9 (18)
Report on the same cohort (e.g. at an earlier follow-up stage)6 (12)
Asthma status inadequately measured (e.g. only uses stress biomarkers)5 (10)
Participants are not asymptomatic at baseline7 (14)
Articles retained for systematic review10 (20)
Total49 (100)