High-resolution computed tomography criteria for UIP pattern as specified in the 2011 ATS/ERS/JRS/ALAT guidelines for the diagnosis of interstitial lung disease

UIP pattern (all four features)Possible UIP pattern (all three features)Inconsistent with UIP pattern (any of the seven features)
Subpleural, basal predominance
Reticular abnormality
Honeycombing with or without  traction bronchiectasis
Absence of features listed as  inconsistent with UIP pattern
Subpleural, basal predominance
Reticular abnormality
Absence of features listed as inconsistent with UIP pattern
Upper or mid-lung predominance
Peribronchovascular predominance
Extensive ground-glass abnormality (extent >reticular abnormality)
Profuse micronodules (bilateral, predominantly upper lobes)
Discrete cysts (multiple, bilateral, away from areas of honeycombing)
Diffuse mosaic attenuation/air-trapping (bilateral, in ≥3 lobes)
Consolidation in bronchopulmonary segment(s)/lobe(s)
  • UIP: usual interstitial pneumonia; ATS: American Thoracic Society; ERS: European Respiratory Society; JRS: Japanese Respiratory Society; ALAT: Latin American Thoracic Association. Reproduced and modified from [3] with permission from the publisher.