Sleep in idiopathic pulmonary fibrosis

Sleep macro- and micro-architectureIncreased stage 1 sleep
Decreased REM and slow-wave sleep
Decreased sleep efficiency
Increased WASO
Increased arousal index
Respiratory patternIncreased respiratory frequency during sleep
Rapid and shallow breathing (especially during REM sleep)
Nocturnal oxygenation parametersEpisodic desaturation during REM sleep
Desaturation during NREM sleep
Desaturation due to respiratory events (apnoeas and hypopnoeas)
Sleep disordered breathingIncreased incidence of obstructive sleep apnoea
Other sleep problemsIncreased periodic leg movements during sleep
Nocturnal cough
  • REM: rapid eye movement; WASO: wake time after sleep onset; NREM: non-REM.