Table 1. Characteristics of the five largest randomised controlled trials testing the role of prone positioning in patient survival
First author [ref.]
Gattinoni [31]Guérin [32]Mancebo [33]Taccone [34]Guérin [2]
Patients n
    Supine position15237860174229
    Prone position15241376168237
Patients with ARDS %
    Supine position93.328100100100
    Prone position94.733.9100100100
PaO2/FIO2 at inclusion mmHg127150147113100
Tidal volume at inclusion mL·kg−110.3 MBW8 MBW8.4 PBW8 PBW6.1 PBW
PEEP at inclusion cmH2O108121010
Prone position session duration# h78171817
Mortality %
    Supine position2531.55832.832.8
    Prone position21.132.4433116
  • ARDS: acute respiratory distress syndrome; PaO2: arterial oxygen tension; FIO2: inspiratory oxygen fraction; PEEP: positive end-expiratory pressure; MBW: measured body weight; PBW: predicted body weight. #: average hours per session.