Table 3. Comparison of characteristics of patients aged ≥19 yrs at diagnosis meeting traditional haemodynamic characteristics of pulmonary arterial hypertension with those with a pulmonary capillary wedge pressure (Ppcw) of 16–18 mmHg
Ppcw at diagnosis
≤15 mmHg16–18 mmHgp-value
Subjects n2525239
Age yrs
    At enrolment53.0±14.056.1±14.50.001
    At diagnosis50.1±14.453.6±14.9<0.001
Female2007 (79.5)174 (72.8)0.016
Time from diagnosis24.9 (8.0–50.9)20.2 (5.5–44.6)0.038
6MWD m366±126339±1170.004
ra mmHg9.3±5.612.8±5.6<0.001
PVRI Wood units·m221.1±12.519.1±13.00.052
Hypertension980 (40.2)111 (47.6)0.023
Obese#697 (33.3)85 (41.9)0.014
Sleep apnoea484 (21.0)85 (39.9)<0.001
Diabetes overall293 (12.0)47 (20.2)<0.001
Renal insufficiency109 (4.5)25 (10.7)<0.001
Cadiomyopathy dilated24 (1.0)4 (1.7)0.286
Warfarin1302 (53.4)105 (45.1)0.016
Oxygen982 (40.3)110 (47.2)0.036
β-blocker296 (12.1)51 (21.9)<0.001
  • Data are presented as mean±sd, n (%) or median (interquartile range), unless otherwise stated. 6MWD: 6-min walk distance; ra: mean right atrial pressure; PVRI: pulmonary vascular resistance index. #: body mass index ≥30 kg·m−2. Reproduced from [15] with permission from the publisher.