| Stage | Treatment strategy# |
| I | Upfront surgery |
| Complete resection Thymoma: no post-operative radiotherapy Thymic carcinoma: consider post-operative radiotherapy | |
| Incomplete resection: post-operative radiotherapy | |
| IIa | Upfront surgery |
| Complete resection Type A-B2 thymoma: no post-operative radiotherapy Type B3 thymoma-thymic carcinoma: consider post-operative radiotherapy | |
| Incomplete resection: post-operative radiotherapy | |
| IIb | Upfront surgery |
| Complete resection Type A-B1 thymoma: no post-operative radiotherapy Type B2-B3 thymoma-thymic carcinoma: consider post-operative radiotherapy | |
| Incomplete resection: post-operative radiotherapy | |
| III–IVa | Resectable tumour Upfront surgery with en bloc resection of the tumour and involved structures Post-operative radiotherapy with boost on areas of concern |
| Unresectable tumour Primary chemotherapy If the tumour becomes resectable: Surgery with en bloc resection of the tumour and involved structures Post-operative radiotherapy with boost on areas of concern If the tumour remains unresectable: Definite radiotherapy | |
| IVb | Definite chemotherapy |
#: expert opinion.