Table 3. Factors affecting daily breathlessness variation in 2,441 patients with severe chronic obstructive pulmonary disease
FactorOR (95% CI)p-value
Age calculated for 10-yr changes0.85 (0.75–0.96)0.0106
Severity of breathlessness
    Moderately versus a little1.47 (1.04–1.95)0.0083
    Very versus a little2.85 (2.06–3.94)<0.0001
    Extremely versus a little2.56 (1.52–4.33)0.0004
Maintenance treatment with only one long- acting bronchodilator (no versus yes)2.06 (1.36–3.13)0.0007
Physician activity (general practitioner versus specialist)1.39 (1.08–1.78)0.0099
  • Reproduced from [63] with permission from the publisher.