Table 6. Meta-analysis of smoking cessation trials in chronic obstructive pulmonary disease patients
StudySubjects nProlonged abstinence rate
Lung Health Study [36]588712 months: 34% versus 9% (NRT)
Hilberink [37]3926 months: 16% versus 9% (NRT)
T├śnnesen [20]37012 months: 14% versus 5% (NRT)
Tashkin [21]4046 months: 16% versus 9% (BUP)
Wagena [38]2556 months: 30% versus 19% (BUP)
Pederson [39]646 months 27% versus 16%
Crowley [40]496 months: 14% versus 14%
Brandt [41]5612 months: 32% versus 16%
Tashkin [22]49912 months: 19% versus 6% (VAR)
  • Data are presented as abstinence rates for intervention versus control groups. NRT: nicotine replacement therapy; BUP: bupropion SR; VAR: varenicline. Reproduced from [35] with permission from the publisher.