Table 5. Double-blind, placebo-controlled randomised smoking cessation studies in chronic obstructive pulmonary disease patients
MedicationSubjects nFEV1 % pred12-month sustained quit rates
ActivePlacebo
Varenicline5057018.65.6
Bupropion SR40472108
NRT37056145

  • FEV1: forced expiratory volume in 1 s; % pred: % predicted; NRT: nicotine replacement therapy. Data from [20–22].