Study 004 | Study 006 | Combined studies | ||||
Pirfenidone 2403 mg·day−1 | Placebo | Pirfenidone 2403 mg·day−1 | Placebo | Pirfenidone 2403 mg·day−1 | Placebo | |
Week 0 | 74.5 | 76.2 | 74.9 | 73.1 | ||
Week 12 | -1.2 | -2.7 | -1.5 | -1.1 | −1.3 | −1.9 |
Week 24 | -1.4 | -3.9 | -1.7 | -4.5 | −1.5 | −4.2 |
Week 36 | -2.6 | -7.2 | -2.5 | -4.9 | −2.6 | −6.1 |
Week 48 | -4.4 | -9.2 | -5 | -6.9 | −4.7 | −8.0 |
Week 60 | -6.6 | -10.7 | -7.4 | -8 | −7.0 | −9.4 |
Week 72 | -8 | -12.4 | -9 | -9.6 | −8.5 | −11.0 |
CAPACITY: Clinical Studies Assessing Pirfenidone in IPF: Research of Efficacy and Safety Outcomes. Data from [24].