Sinusitis of one or more paranasal sinus on radiography |
Necrosed amorphous tissue along with oedematous polyps infiltrated with eosinophils on histopathological evaluation of material from the sinus |
Demonstration of fungal elements in nasal discharge or in material obtained at the time of surgery by stain or culture |
Absence of diabetes, previous or subsequent immunodeficiency disease, and treatment with immunosuppressive drugs |
Absence of invasive fungal disease at the time of diagnosis or subsequently |
Other features |
Peripheral blood eosinophilia |
Type I and type III cutaneous hypersensitivity to Aspergillus |
Precipitating antibodies to Aspergillus antigens |
Elevated total, as well as Aspergillus-specific, IgE levels |
Characteristic computed tomography appearances |