Table 1 Summary of reported cases of primary rhabdoid tumour of the lung
CaseAge yrsSexSymptomsSmoking historyTMN stageMaximum dimension cmLocationSite of metastasesAssociated tumour typeRhabdoid cells %Follow-up status[Ref.]
154FHaemoptysisYesNA8.0≥, ≤1.3RULLymph nodeLarge cell carcinoma90AWD, 6 months11
236MChest painNANA8.0≥, ≤1.3LULNASarcoma>10AWD, 4 months11
347MHaemoptysisYesNA8.0≥, ≤1.3RLLNAAdenocarcinoma>10DOD, 4 months11
471FNANANA8.0≥, ≤1.3LULLymph nodeAdenocarcinoma10AWD, 2 months11
571MNANANA8.0≥, ≤1.3RLLNALarge cell carcinoma>10ASU, 5 months11
625FBazex’s syndromeNoNA8.0≥, ≤1.3LLLLung, lymph nodeLarge cell carcinoma10NA11
774MNoneYesNA3.5LLLNANAMostANED, 24 months12
868MCough, haemoptysisNANA3RMLLymph nodeAdenocarcinoma>10DOD, 6 months13
962FCough, haemoptysisYesNA11RULPresentLCNEC25DOD, 3 months13
1040MCough, chest pain, dyspnoeaYesNA6RULNAAdenocarcinoma>10LFU, 6 months13
1150FCough, dyspnoeaYesNA17LLLLymph nodeLCNEC, small cell carcinoma15DOD, 6 months14
1253MCough, fatigueYesNA12LULNALCNEC, small cell carcinoma, SCC10DOD, 12 months14
1351MHaemoptysisYesIIIA4RULLymph nodeAdenocarcinoma70DOD, 36 months15
1472MCoughNoIIIA5.6RULLymph nodeAdenocarcinoma90DOD, 4 months15
1550FFatigueNoIA3.0RMLNAAdenocarcinoma50ASU, 41 months15
1669MNoneNAIIIA4.5RLLNonePoorly differentiated tumour18.2DOD, 1.5 months8
1766MHaemoptysisNAIIIB6.0LULNonePoorly differentiated tumour15.5DOD, 0.6 months8
1882MCough, chest pain, dyspnoeaYesIIIA11.0LULNonePoorly differentiated tumour15DOD, 18
1947FCough, haemoptysisYesIIIA8.5RULNonePoorly differentiated tumour60DOD, 10 months8
2069FChest painYesNA2.0RULDuodenum, skin adrenal glandPseudomesotheliomatous adenocarcinomaNADeath, other disease; 3 months16
2159MNAYesNA4.5RULAdrenal glandLarge cell carcinoma90ANED, 60 months17
2270FNoneNAIB9LLNoneLarge cell carcinomaPure LCCRPANED, 8 months18
2357MRespiratoryYesNA23.0LULNot knownSarcomatoid carcinoma25LFU, NA7
2457FHaemoptysisYesI4.0LULBrain, jejunumLarge cell undifferentiated carcinoma90DOD, 11 months7
2554MHaemoptysisYesIV4.0RULLiver, bone, lymph, nodeLarge cell undifferentiated carcinoma15DOD, 4 months7
2648FHoarsenessYesIIIB5.1RULLung, lymph nodeAdenocarcinoma10DOD, 19 months7
2754MHaemoptysis, GI bleedingNAIV10RULBowel, soft tissue, lymph nodeLarge cell undifferentiated carcinoma90DOD, 5 months7
2870MNoneYesIVNALeft lungBone, chest wallAdenocarcinoma90DOD, 10 months7
2961MHaemoptysisYesIIIA4.7RULBone, lymph nodeSarcomatoid carcinoma30DOD, 1.5 months7
3059FCoughYesIVNARMLBrain, bone, lung, lymph nodeAdenocarcinoma50DOD, 3 months7
3134MHaemoptysisNAIV2.0LLLLungSarcomatoid carcinoma60DOD, 3 months7
3265MNoneNAIVNALLLChest wallSarcomatoid carcinoma75LFU, NA7
3359FHaemoptysisYesIIIA3.0LLLLymph nodeAdenocarcinoma20ANED, 20 months7
3455MCough, haemoptysisYesIV3.5LULLiver, spleenLarge cell carcinomaPure LCCRPDOD, 2 months19
3550MChest painNAI8RULNoneLarge cell carcinomaNGSASU, NA20
3658MCough, chest pain, dyspnoeaNAI3LLLNoneLarge cell carcinomaNGSASU, NA20
3756MChest pain, weight lossNAI4RLLNoneLarge cell carcinomaNGSLFU, NA20
3863MCough, chest pain, weight lossNAI4.8RULNoneLarge cell carcinomaNGSAWD, NA20
3937MCough, haemoptysis, back painYesIIIB5RULSmall intestine, lymph nodeLarge cell carcinomaNADOD, 6 months21
4073FRectal bleedingYesIVNANAColonNANADOD, 4 months2
4136FHaemoptysisNoIB6LULLiver, lymph nodeLarge cell carcinomaNAAWD, 62 months1
4263MIntussusceptionYesIV9.5RLLSmall intestine, lymph nodePoorly differentiated tumour80DOD, 1 monthsPresent case report
  • F: female; M: male; NA: not available; GI: gastrointestinal; RUL: right upper lobe; LUL: left upper lobe; RLL: right lower lobe; LLL: left lower lobe; RML: right middle lobe; LCNEC: large cell neuroendocrine carcinoma; SCC: squamous cell carcinoma; LCCRP: large cell carcinoma of the lung with rhabdoid phenotype; NGS: no evidence of glandular and/or squamous differentiation; AWD: alive with disease; DOD: dead of disease; ASU: alive, status unknown; ANED: alive with no evidence of disease; LFU: lost to follow-up.