Table 1. Characteristics of pulmonary arterial hypertension according to New York Heart Association/World Health Organization functional class (NYHA/WHO FC) at diagnosis
ParameterNYHA/WHO FCp-value
6MWD n13435955
    Distance m415±86319±92192±96<0.0001
Haemodynamic variables n16240577
    Pra mmHg6±49±511±7<0.0001
    pa mmHg50±1756±1556±130.0002
    Ppcw mmHg8±38±38±40.75
    Cardiac index L·min−1·m−22.9±0.92.4±0.72.1±0.8<0.0001
    PVRI mmHg·L·min·m−215.8±9.721.5±9.825.5±10.1<0.0001
  • Data are presented as mean±sd, unless otherwise stated. 6MWD: 6-min walk distance; Pra: right atrial pressure; pa: mean pulmonary arterial pressure; Ppcw: pulmonary capillary wedge pressure; Sv,O2: venous oxygen saturation; PVRI: pulmonary vascular resistance index. Reproduced from [10] with permission from the publisher.