Table 1 Eligibility criteria for lung volume reduction surgery (LVRS) versus lung transplantation in emphysema patients

LVRS	Lung transplantation
Age <75 yrs	Age <65 yrs
FEV₁ >20% to <45% pred	FEV₁ <25% pred
D_L,CO >20% pred	D_L,CO <20% pred
RV >200 % pred	P_a,O₂ <55 mmHg
P_a,CO₂ <55 mmHg	P_a,CO₂ >55 mmHg
P_pa <45 mmHg	Pulmonary hypertension/cor pulmonale
Heterogeneous emphysema	All types emphysema including α₁-ATD
Upper lobe	Whole lung
Limited exercise capacity	Limited exercise capacity

FEV₁; forced expiratory volume in 1 s; % pred: % predicted; D_L,CO: diffusion capacity of the lung for carbon monoxide; RV: residual volume; P_a,O₂: arterial partial oxygen pressure; P_a,CO₂: arterial partial carbon dioxide pressure; P_pa: pulmonary artery pressure; α₁-ATD: α₁-antitrypsin deficiency.