Organisation, year | Term | Definition |
ERS, 1999 | Difficult asthma | Asthma remaining uncontrolled despite high-dose inhaled glucocorticosteroids with or without systemic glucocorticosteroids |
Uncontrolled asthma | Persistent asthma symptoms or recurrent exacerbations | |
ATS, 2000 | Severe refractory asthma | According to an ERS Task Force including criteria that specifies asthma control |
WHO, 2010 | Addition of responsiveness to treatment and future risk as a marker for asthma control | |
IMI, 2011 | Poorly controlled asthma | Algorithm to distinguish difficult-to-control asthma from severe refractory asthma |
ATS/ERS, 2013 | Latest recommendations on the identification, evaluation and treatment of patients with severe refractory asthma |
ERS: European Respiratory Society; ATS: American Thoracic Society; WHO: World Health Organization; IMI: Innovative Medicines Initiative.