Population | Prevalence¶ % | Accuracy % | PPV % | Screening tests/diagnosis | RHC/100 | RHC/diagnosis |
PAH-SSc | 12.5 | 82 | 41 | 8.3 | 30 | 2.5 |
PortoPH | 4 | 81 | 17 | 26.3 | 23 | 6.1 |
PAH-SCD | 0.5 | 80 | 7 | 71.4 | 22 | 15.1 |
PAH-SLE | 0.5 | 80 | 2 | 200 | 20 | 41 |
Idiopathic PAH | 80 | 1 | 500 | 0.2 | 101 |
PPV: positive predictive value; RHC/100: number of right heart catheterisations required per 100 of population screened; RHC/diagnosis: number of right heart catheterisations performed for every patient diagnosed with pulmonary arterial hypertension (PAH); PAH-SSc: PAH associated with systemic sclerosis; PortoPH: portopulmonary pulmonary hypertension; PAH-SCD: PAH associated with sickle cell disease; PAH-SLE: PAH associated with systemic lupus erythematosus. #: assumptions: 96% sensitivity; 80% specificity. ¶: assumed for each population based on available literature and may be underestimates.